SARS-CoV-2 Spreads Fast, Similar to Influenza

Coronavirus chain of transmission is less than 1 week
hand shking with COVID-19 written on top

Infectious disease researchers at The University of Texas at Austin (UT Austin) studying the novel coronavirus SARS-CoV-2 were able to identify how quickly the virus can spread.

This is important information that may help public health officials in their efforts at containing the worldwide outbreak.

These UT Austin researchers found that time between cases in a chain of transmission is less than a week and that more than 10 percent of patients are infected by somebody who has the virus but does not yet have symptoms.

Published in the journal Emerging Infectious Diseases, a team of scientists from the United States, France, China, and Hong Kong was able to calculate what’s called the serial interval of the virus. 

To measure serial interval, scientists look at the time it takes for symptoms to appear in two people with the virus: the person who infects another, and the infected second person.

These researchers found that the average serial interval for the novel coronavirus in China was approximately 4 days. 

This also is among the first studies to estimate the rate of asymptomatic transmission.

The speed of an epidemic depends on two things:

  • how many people each case infects, called the Reproduction Number
  • how long it takes for infection between people to spread,  the serial interval.

The short serial interval of COVID-19 disease means emerging outbreaks will grow quickly and could be difficult to stop, the researchers said.

“Ebola, with a serial interval of several weeks, is much easier to contain than influenza, with a serial interval of only a few days. Public health responders to Ebola outbreaks have much more time to identify and isolate cases before they infect others,” said Lauren Ancel Meyers, a professor of integrative biology at UT Austin, in a press release. 

“The data suggest that this coronavirus may spread like the flu. That means we need to move quickly and aggressively to curb the emerging threat.”

Meyers and her team examined more than 450 infection case reports from 93 cities in China and found the strongest evidence yet that people without symptoms must be transmitting the virus, known as pre-symptomatic transmission. 

According to the paper, more than 1 in 10 infections were from people who had the virus but did not yet feel sick.

Previously, researchers had some uncertainty about asymptomatic transmission with the coronavirus. This new evidence could provide guidance to public health officials on how to contain the spread of the disease.

“This provides evidence that extensive control measures including isolation, quarantine, school closures, travel restrictions and cancellation of mass gatherings may be warranted,” Meyers said. 

“Asymptomatic transmission definitely makes containment more difficult.”

Meyers pointed out that with hundreds of new cases emerging around the world every day, the data may offer a different picture over time. Infection case reports are based on people’s memories of where they went and whom they had contact with. If health officials move quickly to isolate patients, that may also skew the data.

“Our findings are corroborated by instances of silent transmission and rising case counts in hundreds of cities worldwide,” Meyers said. 

“This tells us that COVID-19 outbreaks can be elusive and require extreme measures.”

Zhanwei Du of The University of Texas at Austin, Lin Wang of the Institut Pasteur in Paris, Xiaoke Xu of Dalian Minzu University, Ye Wu of Beijing Normal University and Benjamin J. Cowling of Hong Kong University also contributed to the research. 

Lauren Ancel Meyers holds the Denton A. Cooley Centennial Professorship in Zoology at The University of Texas at Austin.

The research was funded by the U.S. National Institutes of Health and the National Natural Science Foundation of China.

For more information, contact: Esther Robards-Forbes, College of Natural Sciences, 512-232-0654.

Coronavirus outbreak news published by Precision Vaccinations.